Aquatio Cave Luxury Hotel and Spa

Set in the center of the sassi, a UNESCO World Heritage Site, this charming 35-room "cave" hotel is an excellent place to stay while experiencing one of the oldest cities in the world. Some of the guestrooms have been dug into the tufa stone, while others are masonry-built with wooden roofs, but all are bright with modern furnishings. There is also a spa (in a cave, of course), with a swimming pool carved right into the rock.